Personal Statement
Over the last 25 years, my work has focused on relationships between stress and health in several risk groups (spouse caregivers of persons with Alzheimer’s disease, medical students, psychiatric/medical outpatients/inpatients, air traffic controllers, and camp counselors). We have developed and/or revised measures of medical student stress, caregiver burden, patient anger/dyscontrol, process coping, appraisal, neuropsychological function and physician awareness of patient problems. These measures have been used by university researchers, insurance companies, pharmaceutical companies in clinical trials, prisons, nursing homes/long term care, rehabilitation facilities, and public health organizations. These psychosocial and behavioral measures have been shown to predict and be predicted by physiological and cognitive measures. We have also focused on moderators of such relationships, such as gender, personality, and co-morbidities. We have used primarily multicohort long-term studies that allow for interactions between exposures to stressors, hard-wired vulnerabilities, and more temporal resources. We attempted to identify mechanisms that can be potentially altered to have long-term public health significance in persons under chronic stress. I have also attempted to isolate groups that are at high risk for negative outcomes. In a perfect world, interventions should be used to help all persons who have deleterious responses to stress, but society cannot afford this. For this reason, the identification of high risk groups is imperative for maximizing the effect of interventions.
My research program’s long range goal is to better understand the mechanisms by which chronic stress translates into physical, mental, or cognitive health problems. We are examining caregivers of spouses with AD and demographically-similar spouse non-caregivers across time and assessing the degree to which elevated depression, stress hormones, inflammation, and insulin resistance in caregivers predict cognitive decline in caregivers relative to non-caregivers. We are also attempting to replicate our earlier work that showed that chronic stress and chronic disease moderate each other’s physiological risks. For example, physiological dysregulation that is specific to a disease (e.g., metabolic syndrome with CHD, blood pressure reactivity with hypertension, and immune function with cancer history, HbA1c with diabetes) is exacerbated in caregivers with a chronic disease relative to non-caregivers with a chronic disease, but no such differences occur in caregivers versus non-caregivers without a chronic disease. Finally, we are examining a large cohort of older adults sampled from various U.S. communities in order to assess the influence of life stressors on long term cognitive function and potential mediators of such changes.
Personal Statement
My career goal is to give suicidal clients and their clinicians the best chance to succeed. I have been working in the area of health services, treatment development, and clinical trials research to prevent suicide for over 30 years. My graduate training was in community/clinical psychology and focused on achieving clinical ends through prevention and other systemic interventions in socio-culturally diverse populations. I have brought these perspectives into health services research. I have developed or adapted interventions to improve care and clinician willingness to work with suicidal patients including Caring Contacts, Dialectical Behavior Therapy (DBT), Collaborative Assessment and Management of Suicidality (CAMS), and Preventing Addiction Related Suicide (PARS). I have developed an adaptation of DBT Next Steps, a program to assist psychiatrically disabled individuals find and maintain living wage employment. My research has been funded by NIMH, NIDA, the Department of Defense, American Foundation for Suicide Prevention, and the State of Washington.
I am the director of the Center for Suicide Prevention and Recovery (CSPAR) whose mission is to promote the recovery of suicidal individuals and the effectiveness and well-being the clinicians and families who care for them by conducting rigorous and ecologically valid research, developing innovative interventions, improving policies, systems and environments of care, and providing expert training and consultation. CSPAR faculty and staff seek a deep understanding of the cultures and settings in which we work that leads to meaningful and effective interventions ready for implementation.
I also direct the Suicide Care Research Center, an NIMH P50 funded research center focused on using Human Centered Design and MOST optimization methodology to improve the care of adolescents and young adults (age 13-30 years) in outpatient medical settings. We are conducting one fully powered trial, three R34s, and 4 pilot studies within UW Medicine and Seattle Children’s hospital to develop innovative interventions to support primary care, Collaborative Care, and specialty medical clinics care for patients experiencing suicidal thoughts and behavior. The center supports effort of over 20 faculty and 16 staff as well as 11 emerging and advanced collaborating scholars and funds 2 annual pilot grants (each $100,000 over two years).
In addition to clinical research, I founded the Society for Implementation Research Collaboration (SIRC) focused on disseminating and implementing innovative, evidence-based interventions in the systems that need them. Beyond my research, I directed the Harborview Dialectical Behavior Therapy program at Harborview Medical Center 1996-2019, co-lead the UWAnnual Comprehensive DBT Training Program and Suicide Care in Healthcare Systems: We Can Do Better Serving our Patients and Caring for our Clinicians, both of which meet the Washington State requirement for suicide prevention training. I have a long history of training and mentoring junior faculty, post-doctoral scholars, psychiatry residents, pre-doctoral psychology interns, undergraduate students, and post-baccalaureate trainees. I provide psychotherapy and consultation at the UWMC Outpatient Psychiatry Clinic.
Personal Statement
Over the past 20 years, my research has focused on the genetics of schizophrenia and neurodegenerative disorders, particularly on the use of clinical phenotyping and innovative genomic technologies to elucidate the complex genetic architecture underlying schizophrenia and Alzheimer’s disease (AD). I served as the Director of the Geriatric Research, Education, and Clinical Center (GRECC) at the VA Puget Sound Health (VAPS) from 2011-2022, in order to focus on my research on Alzheimer’s Disease and related disorders. My current research interests are two-pronged: 1) develop machine learning models in VA’s vast electronic health records in order to assign ADRD probability scores in older Black and White Veterans; and 2) use mobile health devices to promote early diagnosis of dementia with Lewy bodies. In In these capacities, I direct multidisciplinary efforts to better understand the biology, genetics, etiology, prevention, and treatment of these disorders, and I provide clinical expertise for the differential diagnosis of neurodegenerative disorders and treatment of behavioral disturbances in dementias.
Personal Statement
Myra Parker, JD, PhD is an Associate Professor of Psychiatry and Behavioral Sciences, and Director of Seven Directions: A Center for Indigenous Public Health, based within the Center for the Study of Health and Risk Behaviors, University of Washington. She received her doctorate in Health Services at UW School of Public Health, and has been a member of the faculty since 2014.
Dr. Parker’s research and clinical interests include: (1) cultural adaptation of alcohol and drug interventions among American Indians and Alaska Natives (with a particular focus on tribal college drinking harm reduction), (2) development and testing of parenting interventions to support early childhood development in American Indian and Alaska Native communities, (3) co-morbidity of substance use with depression, suicide, trauma, and PTSD, (4) research capacity development, including ethical aspects of research, for tribal and urban Indian communities; and, (5) dissemination and translation of evidence-based prevention and intervention approaches at the individual, institutional, and community level, including policy development. She has worked with tribal and urban Indian communities across the United States on these topics.
