Assessing need and acceptability of a family intervention for individuals with Opioid Use Disorder

Many people love someone who uses substances in a harmful way and want to help that person. Family members and friends often are key supports in people seeking and staying engaged in treatment and services. At the same time, family members and friends feel like they lack the skills or support to help their loved one effectively. This may be especially true for opioid use disorder, where the strongest evidence for treatment is for medication for opioid use disorder, but families and friends don’t know how to help their loved ones access and stay on these life-saving medications.

Our study will talk with people who are getting medications to treat opioid use disorder and ask about the involvement of their family members and friends in their lives and recovery. We will reach out to these key supports to ask how they would want to do a group-based program to help them develop skills and knowledge to support their loved one’s care. These groups would be delivered by nurses with specialized training in opioid use disorder and treatment. Group content will be based on an existing, evidence-based treatment designed for family members and will help people understand the role of medications in treating opioid use disorder and teach skills to support their loved one.

Implementing contingency management in a supportive housing context to promote resident well-being

Mental health and substance use disorders carry complex needs of living that are often poorly-served by our health systems, which result in immense societal costs. This has prompted federal recognition of supportive housing among the vital conditions that support the long-term recovery and resilience of our citizenry. Supportive housing offers safe living environs where residents access services such as harm reduction supplies and referral to recovery-oriented activities like peer support groups and workplace re-entry programs. To maximize the benefit that residents experience from such services, behavioral health staff working in supportive housing contexts should implement useful psychosocial therapies to spur greater service utilization by residents.

One such therapy that has proven useful among persons with mental health and substance use disorders is contingency management (CM), in which one earns tangible rewards for demonstrating desired behaviors like attending a support group, taking a prescribed medication or completing workplace re-entry paperwork. Given the robust and reliable therapeutic impacts of CM, there is much to be gained from its implementation in supportive housing environs. For several years, the project lead Dr. Hartzler and his team at the UW Center for Advancing Addiction Health Services (CAAHS) have provided comprehensive technical assistance to regional treatment settings to facilitate design and successful implementation of sustainable CM programming. Also, UW project collaborators Drs. Fockele and Leyde have built working relationships with Downtown Emergency Services Center (DESC) while exploring interest in CM among its staff and residents. This convergence of acute community need, an experienced team offering technical assistance and an established academic-community partnership highlights an opportunity in which CM will be implemented in DESC-governed supportive housing facilities to increase resident utilization of beneficial services.      

Improving the implementation of smartphone-based contingency management in medical settings for the treatment of methamphetamine use disorder: a qualitative analysis of patient and clinician experiences

The proposed research is a qualitative analysis of patient and clinician experiences during a pilot study of mHealth-delivered contingency management for the treatment of methamphetamine use disorder and will address perceived facilitators and reinforcing factors, barriers and limitations, and proposals for future improvements including specific recommendations regarding the intervention and its mode of delivery.

Alcohol-focused Support of Survivors In Sororities Training (ASSIST)

The purpose of this study is to develop and evaluate a new online program called ASSIST – Alcohol-focused Support of Survivors In Sororities Training. The training is designed to help sorority members learn how to support friends who have had an unwanted sexual experience, both during the initial discussion of the experience and when navigating recovery in the longer-term. This multiphase study involves (1) developing the training in collaboration with students and campus stakeholders, (2) improving the training content and design through individual interviews with sorority members, (3) conducting an open trial of the training within one chapter, and then (4) conducting a pilot cluster randomized trial to evaluate feasibility and initial efficacy of the training. If found to be effective, this training could be widely disseminated and facilitate positive change in social contexts where survivors recover.

Real-world Experiences of Alcohol and Cognitions over Time (REACT)

The overall aim of the REACT Study is to create and assess smartphone-based cognitive tasks to examine how acute alcohol intoxication affects attention. First, we will adapt laboratory-based cognitive tasks for use on smartphones. To maximize usability, feedback will be gathered in rapid prototyping interviews with young adults. Then, we will evaluate the adapted smartphone tasks in two settings: (1) a controlled laboratory session in which young adults are administered a standard dose of alcohol, and (2) real-world drinking experiences over eight weekends, as measured with phone surveys and a wrist-based alcohol biosensor. Findings are expected to clarify the role of alcohol-related attentional narrowing in real-world behaviors. Results will be used to inform the development of just-in-time adaptive interventions to prevent alcohol-related consequences.

Identity, Resilience, and Interconnection after Stress (IRIS)

The IRIS Study is a longitudinal examination of young adults who have experienced an unwanted sexual experience in the past year, and those who have never had an unwanted sexual experience. This study aims to prospectively examine how young adults’ thoughts about a recent unwanted sexual experience are shaped by and influence social relationships and health-related behaviors over time. To do so, this multimethod study involves in-depth interviews, social network assessments, ecological momentary assessments, transdermal alcohol biosensors, and online surveys over one year. This study is conducted by researchers at both the University of Washington and the University of Nebraska-Lincoln.

THRIVE Study

This is a study of an app intended to support recent sexual assault survivors, called THRIVE. In a prior grant, we pilot tested THRIVE and found that it reduced risk for alcohol misuse and posttraumatic stress. In the first year of this grant, we aim to revise the app to increase usability and inclusivity. In the second through fifth years of the grant, we will conduct a larger randomized controlled trial of multiple versions of the app among college students who have experienced sexual assault in the past 12 weeks. This will allow us to identify the most effective and low-burden version of THRIVE. If we are successful in identifying a highly effective and efficient version of THRIVE, this intervention would represent a highly-scalable strategy to reduce the substantial burden of posttraumatic stress and alcohol misuse on student survivors and campus service systems.

Health Outcomes of Betting on Sports (Project HOBS)

Project HOBS is examining associations between sports betting, mental health, and substance use among young adults. Surveys are collected bi-weekly for one calendar year (25 follow-ups) and at a distal 15-month follow-up.

Machine learning methods for identifying person-level mechanisms of alcohol use among sexual and gender minority intersections

The goals of the proposed research are to 1) distinguish sexual and gender minoritized (SGM) subgroups and intersections at heightened risk for alcohol use (AU; e.g., bisexuals and trans persons, SGM young women of color), 2) assess the role of state policies in moderating AU risk, and 3) delineate moderators and mechanisms of heightened AU across SGM populations within and beyond the coronavirus pandemic. Aim 1 will identify heterogeneity in substance use behaviors among SGM communities. It will then test race/ethnicity and age as intersectional moderators of SGM inequities and state-level policies impacting SGM communities that further differentiate AU risk among SGM groups. Findings will then be extended to address mediators and moderators of AU in the monthly AURP COVID-19 Participant Experience Survey (Aim 2) as well as the longitudinal, biennial data that extends beyond the pandemic into 2027 (Aim 3).

COVID-19 pandemic and changes in the prevalence, patterns, and trajectories of substance use and related health risk outcomes among young adults in WA State

This project examines changes in young adult substance use, related health risk behaviors, and substance use-related risk factors from before to during the COVID-19 pandemic among young adults in WA state (where alcohol, tobacco, and cannabis sales and use are legal for adults age 21 and over) using the accelerated longitudinal cohort sequential data from the Washington Young Adult Health Study. Findings will inform tailoring and development of prevention and intervention efforts aimed at reducing health risk behaviors and improving public health in emergent situations that pose serious challenges for effective long-term planning of such efforts.