Determining if activity in LHb projections to the RMTg promotes cued reinstatement to fentanyl seeking through indirect inhibition of VTA dopamine neurons

Project Type(s):

Principal Investigator(s):

The main goals of this proposal are twofold: 1) to develop and optimize a general behavioral and technical platform for studying the functional neurocircuitry underlying opioid use disorder, and 2) to determine if activity in LHb projections to the RMTg promotes cued reinstatement to fentanyl seeking through indirect inhibition of VTA dopamine neurons.

Project Period:
May 1, 2021 — April 30, 2022

Funding Type(s):
Federal

Funder(s):
NIDA

Research Program(s):

Targeted Condition(s):
Substance use disorders/misuse