Real-world Experiences of Alcohol and Cognitions over Time (REACT)

The overall aim of the REACT Study is to create and assess smartphone-based cognitive tasks to examine how acute alcohol intoxication affects attention. First, we will adapt laboratory-based cognitive tasks for use on smartphones. To maximize usability, feedback will be gathered in rapid prototyping interviews with young adults. Then, we will evaluate the adapted smartphone […]

COVID-19 pandemic and changes in the prevalence, patterns, and trajectories of substance use and related health risk outcomes among young adults in WA State

This project examines changes in young adult substance use, related health risk behaviors, and substance use-related risk factors from before to during the COVID-19 pandemic among young adults in WA state (where alcohol, tobacco, and cannabis sales and use are legal for adults age 21 and over) using the accelerated longitudinal cohort sequential data from […]


SPARK is an autism research study and a growing community of autistic individuals, their families, and researchers with a goal to advance the understanding of autism. This study aims to improve the lives of people with autism by identifying the causes of autism and informing more effective therapies, treatments, services, and supports.

TIGER: The Investigation of Genetic Exome Research

In the TIGER research study, we are learning more about individuals with genetic events associated with autism spectrum disorder (ASD), intellectual disability (ID), and/or developmental delay (DD) in order to better describe how different gene disruptions impact behavior in children and adults.

Development of a monoclonal antibody to reverse overdose from fentanyl and its analogs: from manufacturing to clinical trials

The widespread availability of fentanyl and other potent synthetic opioids has dramatically increased opioid-related fatal overdoses. This project will develop and manufacture immune molecules (monoclonal antibodies) to reverse and treat overdose from fentanyl by keeping it out of the brain. This research will advance promising results in animal studies (preventing and reversing fentanyl- and carfentanil-induced […]

Parent and teacher engagement as an undervalued implementation determinant

The proposed research addresses three important objectives (1) complete a scoping review to map determinants of teacher implementation of evidence-based practices for child behavior in preschool , (2) identify strategies to improve teacher implementation through a series of casual pathway diagrams, and (3) conceptualize and operationalize strategies with stakeholders to increase feasibility.

Improving diagnostic imaging to guide treatment of neuroinflammation

Infection by West Nile Virus can lead to encephalitis, or harmful inflammation of the brain. The immune system is critical for controlling viral replication and spread early in West Nile Virus infection, but persistent immune activation causes encephalitis that can result in brain damage even after the virus has been cleared. Recent pharmacologic advances have […]

Modeling patient mutations in iPSC-derived neurons to reveal cellular mechanisms of schizophrenia

Schizophrenia is a common and devastating neurodevelopmental disorder characterized by genetic heterogeneity. In this project, genes that are disrupted by rare, damaging mutations in individuals with schizophrenia will be evaluated using CRISPRi in iPSCs. Cell lines will be evaluated for phenotypes relevant to schizophrenia. A patient-derived iPSC line will be created that harbors a mutation […]

Latinx Health in Rural Areas (Project LAHRA)

This project aims to examine health disparities in substance use and factors influencing the health and well-being of Latinx youth residing in rural and small-town communities of the United States, a growing but understudied and underserved population.