Deaths related to the opioid overdose epidemic remain at an all-time high
across the country despite significant efforts to reduce them. There is a
pressing need to support medication treatment for opioid use disorder (OUD) to
help people stay in treatment and reduce the risk of overdose death and other
serious health consequences of untreated addiction. Smartphone-based apps can
facilitate the delivery of an evidence-based approach called contingency
management that incentivizes use of medications for OUD, reduces use of
non-prescribed opioids and improves retention in OUD treatment.
This study will leverage a commercially available smartphone app that can
bring this much-needed behavioral support to patients receiving OUD treatment
in a primary care clinic and in a specialty OUD treatment clinic. The approach
offers a potentially non-labor intensive, cost-effective and highly scalable
means of delivering OUD care.
This research develops and tests digital technology to help clinicians and patients systematically measure and monitor clinical progress during addiction treatment. The technology is being developed based on end-user input and user-centered design methods and will be pilot tested as an add-on to real-world care in an addiction treatment clinic.
This small business technology transfer grant will test the feasibility and usability of a smartphone mHealth tool that allows for video directly observed therapy of methadone and remote screening for COVID-19 symptoms.
This project will create a mentored research training program for University of Washington medical students to engage in substance use disorder-focused research and clinical practice during their medical school training.
This project will integrate and analyze datasets from multisite clinical trials of alcohol use disorder treatments to understand alcohol addiction research domain criteria (AARDoC) phenotypes and biopsychosocial predictors of alcohol use disorder recovery up to three and ten years following treatment.
Perinatal depression affects 10-15% of pregnant and postpartum individuals, with detrimental impacts on both parent and infant. In response to this, our department developed a perinatal consultation line for providers, PAL for Moms, to increase access to specialty perinatal psychiatric expertise and care. The purpose of the Evaluating Lifeline4Moms (ELM) is to assess comparative effectiveness of PAL for Moms and other perinatal psychiatry access and referral programs in addressing maternal depression.
As a community-engaged research endeavor, ELM has convened
patient advocates, policy experts, and perinatal clinicians, who oversee the
study as partners and advisors. Over a period of three years, the research team
will characterize the components, implementation timelines, and state policy
contexts of access and referral programs; evaluate the reach and implementation
of these programs; and examine the comparative effects on access to and quality
of mental health treatment among Medicaid-insured perinatal individuals.
Moderate to severe traumatic brain injury (TBI) is a common cause of long-term disability. Persons with TBI receiving care in inpatient rehabilitation facilities (IRFs) are at risk for rehospitalization, poor community reintegration, family stress, and other unfavorable outcomes. In a six-center randomized pragmatic comparative effectiveness study, we compare the effectiveness of two methods for transition from IRF to the community. The Rehabilitation Discharge Plan (RDP) includes patient/ family education and referrals for continued care. The Rehabilitation Transition Plan (RTP) provides RDP plus individualized, manualized care management via phone or videoconference. 900 patients will be randomized, with caregivers also invited to participate. Assessed outcomes include societal participation, quality of life, caregiver well-being, and use of healthcare resources at 6-months and 12-months post-discharge.
This project aims to improve the treatment of depression in cancer patients. Up to 25% of people with cancer will become clinically depressed, significantly affecting their quality of life, functioning, and ability to tolerate cancer treatment. Unfortunately, about 75% of cancer patients with depression do not receive adequate treatment, and patients in rural settings are even less likely to receive adequate care. This study uses a human-centered design approach to develop, build, and test a web and mobile platform to enhance the implementation and fidelity of collaborative care management (CoCM) of depression for patients being treated at urban and rural cancer centers. In Phase I, patient-facing web and mobile applications and a clinician facing website will be developed. In Phase II, the technology-enhanced system will be compared to usual CoCM in a pragmatic effectiveness-implementation randomized controlled trial.
To evaluate the use of an existing selective suicide prevention intervention, Preventing Addiction Related Suicide (PARS), for use with Veterans by: 1) adapting and tailoring content to Veteran populations and 2) conducting an open trial within a VA substance use disorder intensive outpatient program.
The Stepped Care for Opioid Use Disorder Train-the-Trainer (SCOUTT) program is a national VA initiative which aims to improve access to treatment medications for opioid use disorder (OUD) in primary care, pain management, and mental health clinics. The Seattle CESATE is conducting ongoing evaluations of SCOUTT to understand providers’ perspectives on the initiative and the outcomes for Veteran participants. Project aims also include to: assess patient retention in and compliance with SCOUTT, assess changes in number of waivered and prescribing providers, retention in and compliance with stepped care, and identify barriers and facilitators to implementing, sustaining and spreading OUD care.
