This A-START award included the conduct of secondary analyses of the national CNICS HIV care database to examine the prevalence and impact of substance use disorders on HIV care indices, and a mixed-method study of the contextual readiness of regional HIV care settings for empirically-supported behavior therapies.
Funding Type: Federal
Integrating Behavioral Interventions in Substance Abuse Treatment
This mentored career development award funded the conduct of two studies to inform efforts to disseminate and implement contingency management (CM): 1) a mixed-method study of CM attitudes and practices among personnel at a nationwide sampling of 16 community-based opioid treatment programs; and 2) a pilot type III hybrid effectiveness/implementation trial examining strategies for implementing CM programming customized to local OTP needs/resources.
Latinx Health in Rural Areas (Project LAHRA)
This project aims to examine health disparities in substance use and factors influencing the health and well-being of Latinx youth residing in rural and small-town communities of the United States, a growing but understudied and underserved population.
Cannabis legalization and changes in young adult substance use, related health risk behaviors, and risk factors in WA State (Project YAM)
This project involves analyses of data from the Washington State Young Adult Health Study to examine the impact of cannabis legalization on cannabis-related risk factors, substance use, and related health risk behaviors such as driving while intoxicated, and to study developmental trajectories of substance use and the role of community level and other cannabis-specific risk factors in the context of legalized cannabis among young adults in Washington State.
Project Reflect
This project examines marijuana-specific self-regulation processes in relation to marijuana use and consequences both across days and throughout the day to identify how psychological states and contextual factors influence these self-regulation processes using an EMA design with surveys four times a day for two weeks.
Exploring mechanisms of change in a pilot trial of the RUBI Program in educational settings
The purpose of this study is to: 1) compare schools randomized to the RUBIES intervention or a usual-care in-service training on teacher burnout and disruptive behavior in children with autism spectrum disorder; and 2) test RUBIES’ mechanisms of change (knowledge and skills) on teacher (burnout), child (disruptive behavior), and implementation outcomes (fidelity).
High potency cannabis policy legislative report
| Explore and suggest policy solutions in response to the public health challenges of high tetrahydrocannabinol potency cannabis. ADAI will host stakeholder sessions to gain perspectives, seek common ground, evaluate, and assess potential policy solutions culminating in a final recommendation report. |
A brief behavioral intervention for co-users of marijuana and tobacco among smokers calling state quitlines
The major goal of this project is to evaluate the feasibility and effectiveness of an integrated intervention approach for co-users of marijuana and tobacco who are seeking treatment for tobacco addiction.
Microglia and opioid withdrawal: mechanisms of negative reinforcement
Extensive opioid use and repeated abstinence increases the likelihood of severe withdrawal and contributes to the risk of relapse. Previously we found that microglia, the innate immune cells in the brain, have dramatic changes in gene expression and signaling during opioid tolerance and withdrawal. We propose to use fentanyl and a recently developed transgenic mice to investigate whether repeated cycles of tolerance and withdrawal aggravate changes in microglial function and whether purinergic receptors in microglial contribute to opioid withdrawal. We will study the microstructure and motility of microglia using time- lapse microscopy and measure real-time changes in cyclic and calcium dynamics. The goal of the project is to identify new targets to treat opioid withdrawal and relapse.
Mobile mental health in community-based organizations: a stepped care approach to women’s mental health
Of every 10 women in rural India, one suffers from a common mental disorder such as depression. For many, depression goes untreated and is associated with increased morbidity and mortality rates. Several factors, specifically for women in rural India, including stigma, lack of provider mental health workforce, and travel times. Therefore, there is an urgent need to improve detection and treatment rates among women without overburdening the scarce mental health resources in rural India.
The “Mobile Mental Health in Community-Based Organizations: A Stepped Care Approach to Women’s Mental Health” study aims to develop and implement a mobile mental health intervention for women through community-based organizations. The intervention is delivered in a stepped-care approach where women receive different levels of intervention depending on the severity of their mental health needs.
