Deidre Jansson, MSc, PhD

Deidre completed her MSc at the University of Ottawa where she studied molecular mechanisms of insulin and calcium signaling in pancreatic beta cells. She completed her PhD in Molecular Neuropharmacology at the University of Auckland, New Zealand where she investigated the role of inflammation and signaling pathway important in human brain pericyte biology. Ongoing projects have branched out to include the use of novel MRI techniques for blood-brain barrier imaging in humans, inflammatory bio marker analysis, as well as ongoing molecular work in human primary cells to identify drug targets for neurodegenerative diseases. New projects in the Iliff lab will surround the role of the choroid plexus in glymphatic clearance, and how this may impact/or be impacted by age-related neurodegeneration.

Recent Publications

Measurement of blood-brain barrier water exchange rate using diffusion-prepared and multi-echo arterial spin labelling: Comparison of quantitative values and age dependence.
(2024 Dec)
NMR Biomed 37(12): e5256
Morgan CA, Thomas DL, Shao X, Mahroo A, Manson TJ, Suresh V, Jansson D, Ohene Y, Günther M, Wang DJJ, Tippett LJ, Dragunow M

Macroscopic changes in aquaporin-4 underlie blast traumatic brain injury-related impairment in glymphatic function.
(2024 Jun 3)
Brain 147(6): 2214-2229
Braun M, Sevao M, Keil SA, Gino E, Wang MX, Lee J, Haveliwala MA, Klein E, Agarwal S, Pedersen T, Rhodes CH, Jansson D, Cook D, Peskind E, Perl DP, Piantino J, Schindler AG, Iliff JJ

The amyotrophic lateral sclerosis-linked protein TDP-43 regulates interleukin-6 cytokine production by human brain pericytes.
(2022 Dec)
Mol Cell Neurosci 123(): 103768
Scotter EL, Cao MC, Jansson D, Rustenhoven J, Smyth LCD, Aalderink MC, Siemens A, Fan V, Wu J, Mee EW, Faull RLM, Dragunow M

Dynamic infrared imaging of cerebrospinal fluid tracer influx into the brain.
(2022 Jul)
Neurophotonics 9(3): 031915
Keil SA, Braun M, O'Boyle R, Sevao M, Pedersen T, Agarwal S, Jansson D, Iliff JJ

Characterisation of PDGF-BB:PDGFRβ signalling pathways in human brain pericytes: evidence of disruption in Alzheimer's disease.
(2022 Mar 17)
Commun Biol 5(1): 235
Smyth LCD, Highet B, Jansson D, Wu J, Rustenhoven J, Aalderink M, Tan A, Li S, Johnson R, Coppieters N, Handley R, Narayan P, Singh-Bains MK, Schweder P, Turner C, Mee EW, Heppner P, Correia J, Park TI, Curtis MA, Faull RLM, Dragunow M

Show complete publication list »
Edit Profile