The ages of 18-25 years are ‘peak onset’ times of major depression and bipolar disorder. These disorders have different courses and treatments, but diagnosing bipolar disorder is difficult because manic symptoms occur less often than depressive symptoms and many individuals do not recall manic symptoms. A ‘misdiagnosis lag’ of 8-10 years can contribute to prolonged […]
Most young adults with mental health (e.g., depression, anxiety) or substance use disorders do not receive treatment. Untreated mental health and substance use can be associated with impairments in social relationships, overall functioning and suicide. National data indicate that almost half of young adults with symptoms of a mental health disorder reported they needed mental health […]
Through a community-partnered approach we will develop and deliver a parent-teacher relationship intervention at local preschools that serve under-represented minority families.
The most salient and debilitating aspect of dementia is memory loss. Unfortunately, memory loss is also the most difficult to quantify because it relies on doctor-administered tests that cannot be repeated very often. Without frequent and accurate measurements, it is difficult for clinicians to make reliable diagnoses, for patients and their caretakers to prepare in […]
Alzheimer’s Disease (AD) is a degenerative condition that affected 5.8 million seniors in 2020 and is the sixth leading cause of death in the United States. Detecting mild cognitive impairment, often a precursor to AD, and predicting its advance to AD dementia are key clinical diagnostic problems. Early diagnosis can motivate early intervention with lifestyle […]
Cognitive therapies help patients by providing ways to modify habitual but unproductive thought patterns, known as maladaptive thinking styles. Cognitive therapies are effective in treating depression, amongst other conditions, and are increasingly delivered remotely as text-based interventions. This trend toward digital delivery has accelerated on account of physical isolation and psychological stressors during the global […]
Schizophrenia is a debilitating mental health condition with high societal and personal costs, due largely to chronic difficulties with social and occupational functioning. While classical symptoms of schizophrenia – such as hearing voices – are often responsive to medication, people with schizophrenia also experience difficulties in social cognition, or understanding and interpreting the intentions and […]
UW Medicine has amassed detailed patient treatment and business data in its electronic medical record (EMR). This information is a treasure trove that is not used to its full potential for two reasons: 1) For each clinical encounter, only a fraction of the information in the EMR is relevant, and virtually all of the information […]
Following severe cases of traumatic brain injury (TBI), the brain can swell, leading to elevations in intracranial pressure (ICP). Patients who develop high ICP following severe TBI are more likely to have poor neurologic recovery from their injury, and control of ICP likely contributes to improved outcomes. ICP detection and management is typically guided by […]
Positron emission tomography (PET) is an imaging technique that uses radioactive substances to visualize and assess the brain function. Apart from its heavy use in clinical oncology, PET is widely used in a variety of other conditions such as various neurological, psychiatric, neuropsychological, and cognitive disorders and is the gold standard for assessing neurodegeneration. In […]