Making generative AI safe for people with mental health conditions

Hundreds of millions of people are already using Large Language Models (LLMs), including for mental health purposes, which has led to inadvertent harms. Critically, people with mental health conditions may be especially vulnerable to such harms. In this project, we will develop the first computational framework to systematically quantify and benchmark the risks that LLMs […]

Evaluating large language models in conveying determinants of mental health

This project aims to evaluate LLMs’ bias and accuracy in conveying the causes of mental health disorders (e.g., anxiety). We will address the absence of related data and the challenge of annotating data by responsibly collecting human-LLM conversations about mental health advice and working with domain experts to create fact sheets about mental health conditions’ […]

Optimizing telemental health with live artificial intelligence clinical scaffolding and feedback

This project aims to develop a clinical scaffolding system to enhance telemental health care by providing real-time coaching and actionable suggestions during video-based sessions. Modeled after live supervision methodologies, it supports clinicians by identifying intervention targets and offering text-based coaching prompts to guide care. Unlike automated chatbots, this approach enables clinicians to adapt suggestions to […]

Developing a hospital-based treatment engagement program for Alcohol Use Disorder

Alcohol use disorder (AUD) frequently results in serious illness, injuries, and hospitalizations. Surviving illness or injuries related to alcohol use can motivate behavior change that could be harnessed through treatment engagement for AUD in the hospital; however, in general hospital settings, patients are rarely presented with more than a piece of paper with phone numbers […]

Canoe Journey: Land, water, language and culture for youth wellbeing

The Canoe Journey study is an exploratory study aimed at examining the acceptability and fit of motivational interviewing (MI) and dialectical behavioral therapy (DBT) among American Indian and Alaska Native youth and young adult Canoe Journey participants. The team will develop a list of MI and DBT approaches in collaboration with Canoe Journey partners, and […]

CANOE partnership: Cancer Awareness, Navigation, Outreach, and Equitable Indigenous Health Outcomes

The CANOE Partnership: Cancer Awareness, Navigation, Outreach, and Equitable Indigenous Health Outcomes responds to the need to improve cancer outcomes for American Indian and Alaska Native (AI/AN) communities. Our Overall Specific Aims are: (1) Improve rates of cessation of commercial tobacco smoking among a nationally recruited sample of AI/AN adults (Research Project 1); 2) Improve […]

Enhancing Suicide Care Monitoring and Intervention in Primary Care

This project outlines a comprehensive two-year initiative aimed at enhancing suicide care services in primary care settings. The project addresses a critical gap in the continuum of care by providing interim crisis support for at-risk patients who are waiting to be connected to specialty mental health. The main objectives of this project are to develop […]



Deciphering Mechanisms of ECT Outcomes and Adverse Effects (DECODE)

Electroconvulsive therapy (ECT) is one of the most effective antidepressant non-invasive brain stimulation therapies for adults with major depression. However, a number of patients fail to respond despite adequate trials, and while clinically beneficial, ECT can produce adverse cognitive effects including amnesia, executive dysfunction, and verbal dysfluency. In this prospective study, we propose the first […]