
Mark Stein, PhD, ABPP
Personal Statement
I am clinical psychologist and a Professor of Psychiatry and Pediatrics, and a clinical researcher specializing in ADHD throughout the lifespan. I direct the PEARL Clinic (Program to enhance attention, regulation, and learning) at Seattle Children’s. The PEARL Clinic is based on a multidisciplinary and collaborative care model which works closely with PCP’s who refer families to PEARL for evaluation and access to our behavioral group treatment programs and treatment recommendations. The PEARL clinic also provided multidisciplinary training for psychologists, psychiatrists, pediatricians, family medicine physicians, and medical students. The majority of my clinical work involves diagnostic evaluations and consultations for the parents, referring physician, and schools. My research emphasis is on personalizing ADHD treatment, and determining how best to combine and sequence interventions throughout the lifespan for individuals with ADHD. I have assisted in the development of several stimulant and non stimulant medications, and participated in many clinical trials. Currently, we are conducting a study for parents with ADHD who have young children with ADHD symptoms where we are treating the parent with medication and behavioral parent training or behavior parent training. I am also investigating the relationship between genetic factors and ADHD treatment response. Other areas of interest include sleep problems and overlap with ADHD, and novel treatments such as Trigeminal Nerve Stimulation (TNS) and augmentation strategies such as mindfulness and physical exercise or activity level.Education
Medical school: Southern Illinois University - Carbondale
Fellowship: MacLean Center for Clinical Medical Ethics, Chicago
Department Affiliations
Centers/Programs
Other Affiliations
PEARL Clinic, Director – Seattle Children’s Hospital
Training Clinic
Center for Child Health, Behavior, and Development
Brotman Baty Institute
Scholarly Expertise
- Adolescent/young adult
- Attention Deficit Disorder (ADD)
- Behavioral genetics
- Child and adolescent psychiatry/psychology
- Collaborative Care / Integrated Care
- Consult psychiatry/psychology
- Developmental neuroscience
- Ethics
- Health services and health policy
- Measurement-based care
- Medically complex
- Outpatient psychiatry/psychology
- Primary care
- Psychiatric specialties
- Randomized controlled trial
- Settings
- Telemedicine
- Telepsychiatry/psychology
Recent Publications
Diabetes and Acute Care Use Among Patients With Metastatic Prostate Cancer Treated With Androgen Receptor Signaling Inhibitors.
(2025 Jun 12)
JCO Oncol Pract
Liu MA, Raghunathan R, Runcie K, Wang S, Wright JD, Wei AZ, Stein M, Hershman DL
(2025 Jun 12)
JCO Oncol Pract
Liu MA, Raghunathan R, Runcie K, Wang S, Wright JD, Wei AZ, Stein M, Hershman DL
Pasritamig, a First-in-Class, Bispecific T-Cell Engager Targeting Human Kallikrein 2, in Metastatic Castration-Resistant Prostate Cancer: A Phase I Study.
(2025 Jun 1)
J Clin Oncol
Stein MN, Vinceneux A, Robbrecht D, Doger B, Autio KA, Schweizer MT, Calvo E, Medina L, Van Dongen M, Deville JL, Bernard-Tessier A, Ghosh D, Shotts K, Shen F, Jaiprasart P, Chaudhary R, Wu S, Cartee L, Schnepp R, Gaut D, Lauring J, Wang SC, Villalobos VM, Baldini C
(2025 Jun 1)
J Clin Oncol
Stein MN, Vinceneux A, Robbrecht D, Doger B, Autio KA, Schweizer MT, Calvo E, Medina L, Van Dongen M, Deville JL, Bernard-Tessier A, Ghosh D, Shotts K, Shen F, Jaiprasart P, Chaudhary R, Wu S, Cartee L, Schnepp R, Gaut D, Lauring J, Wang SC, Villalobos VM, Baldini C
The Strengths and Weaknesses of Attention-Deficit/Hyperactivity Symptoms and Normal Behaviors Scale (SWAN): Diagnostic Accuracy and Clinical Utility.
(2025 May 13)
J Atten Disord
Alhajji R, Walsh E, Pike KC, Liu FF, Oxford M, Stein MA
(2025 May 13)
J Atten Disord
Alhajji R, Walsh E, Pike KC, Liu FF, Oxford M, Stein MA
Emapalumab for severe cytokine release syndrome in solid tumor CAR-T: a case report.
(2025)
Front Oncol 15(): 1543622
Ruemmele T, Macedo R, Stein MN, Chan HT, Mapara MY, Jacquemont CF, Reshef R
(2025)
Front Oncol 15(): 1543622
Ruemmele T, Macedo R, Stein MN, Chan HT, Mapara MY, Jacquemont CF, Reshef R
Management of Patients with Muscle-Invasive Bladder Cancer Achieving A Clinical Complete Response after Neoadjuvant Therapy: Evidence and Consideration for Active Surveillance.
(2025 Apr 10)
Curr Urol Rep 26(1): 36
Joffe BI, Christin JR, Le Coz C, Pingle SR, Wei AZ, Runcie KD, Stein MN, DeCastro GJ, Anderson CB, McKiernan JM, Lenis AT
(2025 Apr 10)
Curr Urol Rep 26(1): 36
Joffe BI, Christin JR, Le Coz C, Pingle SR, Wei AZ, Runcie KD, Stein MN, DeCastro GJ, Anderson CB, McKiernan JM, Lenis AT
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