Mark Stein, PhD, ABPP

Personal Statement

I am clinical psychologist and a Professor of Psychiatry and Pediatrics, and a clinical researcher specializing in ADHD throughout the lifespan. I direct the PEARL Clinic (Program to enhance ​attention, regulation, and learning) at Seattle Children’s. The PEARL Clinic is based on a multidisciplinary and collaborative care model which works closely with PCP’s who refer families to PEARL for evaluation and access to  our behavioral group treatment programs and treatment recommendations.   The PEARL clinic also provided multidisciplinary training for psychologists, psychiatrists, pediatricians, family medicine physicians, and medical students. The majority of my clinical work involves  diagnostic evaluations and consultations  for the parents, referring physician, and schools. My research emphasis is on personalizing ADHD treatment, and determining how best to combine and sequence interventions throughout the lifespan for  individuals with ADHD.    I have  assisted in the development of several stimulant  and non stimulant medications, and participated in many clinical trials. Currently, we are   conducting a study  for parents with ADHD who have young children with ADHD symptoms where we are treating the parent with medication  and  behavioral parent training or behavior parent training. I am also investigating the relationship between genetic factors and ADHD treatment response. Other areas of interest include sleep problems and overlap with ADHD,  and novel treatments such as Trigeminal Nerve Stimulation (TNS) and augmentation strategies such as mindfulness and physical exercise or activity level.

Education

Medical school: Southern Illinois University - Carbondale
Fellowship: MacLean Center for Clinical Medical Ethics, Chicago

Department Affiliations

Other Affiliations

PEARL Clinic, Director – Seattle Children’s Hospital
Training Clinic

 

Center for Child Health, Behavior, and Development

 

Brotman Baty Institute

Recent Publications

The Incremental Validity of Transdiagnostic Dimensions of Personality and Psychopathology in Predicting Important Psychological Outcomes.
(2026 Sep-Oct)
Clin Psychol Psychother 33(5): e70329
Dowgwillo EA, Kopitz JL, Cao X, Stein MB, Blais M

Blinatumomab administration in the outpatient setting: Safety and health care utilization.
(2026 Aug 15)
Cancer 132(16): e70566
Valtis YK, Frost BF, Nemirovsky D, Derkach A, Chin KK, Salman MY, Boussi L, Ovalle NT, Baxter E, Mercurio A, Stein EM, Geyer MB, Schrag D, Kelkar AH, DeAngelo DJ, Luskin MR, Park JH, Chen EC

Brain Aging in Specific Phobia: An ENIGMA-Anxiety Mega-Analysis.
(2026 Jul)
Hum Brain Mapp 47(10): e70595
Blake KV, Hilbert K, Ipser JC, Han LKM, Bas-Hoogendam JM, Åhs F, Bauer J, Beesdo-Baum K, Björkstrand J, Blanco-Hinojo L, Böhnlein J, Bülow R, Cano M, Cardoner N, Caseras X, Dannlowski U, Fredrikson M, Goossens L, Grabe HJ, Grotegerd D, Hahn T, Hamm A, Heinig I, Herrmann MJ, Hofmann D, Jamalabadi H, Jansen A, Kindt M, Kircher T, Klahn AL, Koelkebeck K, Krug A, Leehr EJ, Lotze M, Margraf J, Muehlhan M, Nenadić I, Peñate W, Pittig A, Plag J, Pujol J, Richter J, Ridderbusch IC, Rivero F, Schäfer A, Schäfer J, Schienle A, Schrammen E, Schruers K, Seidl E, Stark RM, Straube B, Straube T, Ströhle A, Suchan B, Teutenberg L, Thomopoulos SI, Ventura-Bort C, Visser RM, Völzke H, Wabnegger A, Wannemüller A, Wendt J, Wittchen HU, Wittfeld K, Yang Y, Zilverstand A, Zwanzger P, Schmaal L, Aghajani M, Pine DS, Thompson PM, van der Wee NJA, Stein DJ, Lueken U, Groenewold NA

Shared and specific associations of amygdala nuclei volumes with PTSD symptom domains and childhood trauma: An ENIGMA-PGC PTSD mega-analysis.
(2026 Jul 2)
Mol Psychiatry
Mufford MS, van der Meer D, Baird CL, Sun D, LaBar KS, Ramesar R, Hussain A, Abdallah CG, Andrew E, Averill CL, Baker JT, Baugh LA, Blackford JU, Bomyea J, Bryant RA, Ching CRK, Choi K, Cotton AS, Daniels JK, Davenport ND, Davidson RJ, De Bellis MD, Dennis EL, Densmore M, deRoon-Cassini TA, Disner SG, du Plessis S, Etkin A, Fani N, Fercho KA, Fitzgerald J, Geuze E, Gordon EM, Grupe DW, Harpaz-Rotem I, Russel CC, Herzog JI, Hofmann D, Hudson AR, Ipser J, Jahanshad N, Jovanovic T, Kaufman ML, Koch SBJ, Koerte IK, Korgaonkar MS, Krystal JH, Lanius R, Larson C, Lebois LAM, Levy I, Li G, Liberzon I, Logue MW, Magnotta VA, Manthey A, Maron-Katz A, May G, McLaughlin KA, Mueller SC, Nawijn L, Nelson SM, Neria Y, Neufeld RWJ, Nitschke JB, O'Leary EN, Olatunji BO, Olff M, Olson EA, Peverill M, Phan KL, Pineda E, Ressler KJ, Rosso IM, Salminen LE, Meltzer K, Schmahl C, Seedat S, Sharp CA, Shenton ME, Sierk A, Simons RM, Simons JS, Sponheim SR, Stein MB, Stevens JS, Straube T, Suarez-Jimenez B, Théberge J, Thomopolous SI, van der Wee NJA, van der Werff SJA, van Erp TGM, van Rooij SJH, van Zuiden M, Veltman DJ, Vermeiren RRJM, Walter H, Wang X, Wang L, Xie H, Zhu X, Zhu Y, Thompson PM, Andreassen OA, Stein DJ, Morey RA, Dalvie S

Global Socioeconomic Context and Brain Ageing in Epilepsy: an ENIGMA-Epilepsy study.
(2026 May 1)
medRxiv
Pardoe HR, Devinsky O, Bbiomed Hons JR, Ireland M, Absil J, Altmann A, Alvim MK, Arienzo D, Ballerini A, Barbi E, Bartolini E, Bauer T, Bernasconi A, Bernasconi N, Bernhardt B, Blackmon K, Bonanni P, Bonilha L, Bosco P, Bunyamin J, Caligiuri ME, Cendes F, Christin R, Concha L, Courtney MR, Cruces RR, Danieli A, Davis KA, Depondt C, Dugan P, Duma GM, Duncan JS, Engel J Jr, Atuesta CF, Focke NK, Fortunato F, Gagliardo C, Galovic M, Gambardella A, Gholipour T, Gleichgerrcht E, Guerrini R, Gule MV, Heide EC, Inati S, Ives-Deliperi V, Jackson GD, Jacobs S, Jahanshad N, Kleen JK, Kotikalapudi R, Koubeissi MZ, Labate A, Larivère S, Lenge M, Martins H, Mascalchi M, Meletti S, Moloney PB, O'Brien TJ, Owens-Walton C, Parodi C, Riva A, Roth RW, Royer J, Rüber T, Saba L, Sammarra I, Scárdua-Silva L, Schubert KM, Sepeta L, Severino M, Sinclair B, Sinha N, Staba RJ, Stein DJ, Stein JM, Stoub TR, Striano P, Surges R, Terziev R, Thomopoulos SI, Tondelli M, Tortora D, Vacca S, Vaudano AE, Vivash L, Williams KC, Yasuda CL, Zhang Z, Kaestner E, Thompson PM, Sisodiya SM, McDonald CR

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