Gregory Simon, MD, MPH

Personal Statement

I bring a practical approach to mental health research, working to break down barriers between research and real-world health care.

Education

B.A. Rice University May, 1978
M.D. University of North Carolina May, 1982
M.P.H. University of Washington May, 1990
Intern Internal Medicine University of Washington Hospitals 6/82-6/83
Resident Internal Medicine University of Washington Hospitals 7/83-6/85
Resident Psychiatry Massachusetts General Hospital 7/85-6/88
Fellow Robert Wood Johnson Clinical Scholars Program University of Washington 7/88-7/90

Recent Publications

A phase 1 randomized controlled trial to evaluate the safety and immunogenicity of a HIV monomeric gp120 protein B-cell lineage targeting HIV vaccine in healthy adults.
(2026 May 27)
medRxiv
Kobie JJ, Williams WB, Hahn WO, Edlefsen PT, Isaacs MB, Miner MD, Parks KR, De Rosa SC, An H, Yurdadon C, Spreng J, Hwang J, Clark M, Jain V, Gregory SG, Berry M, Wiehe K, Goepfert PA, Tieu HV, Keefer MC, Baden LR, Kalams S, Morgan C, Montefiori DC, Ferrari G, Regenold S, Tomaras GD, McElrath MJ, Corey L, Sobieszczyk ME, Haynes BF, HVTN 115 Study Team

Nudging provider adoption of clinical decision support: study protocol for a stepped-wedge cluster randomized, hybrid type III trial of an electronic health record-agnostic pulmonary embolism risk tool.
(2026 May 25)
Implement Sci
Khan S, Thomas Y, Garg N, Genes N, Simon GW, Cleland CM, Mir U, Dauber-Decker KL, Solomon JN, Shunk A, Xu L, Mastrianni A, Cui Y, Henning N, Diefenbach MA, McGinn T, Richardson S

Interleukin-34-Induced Arg1+ Macrophages Play a Key Role in Breast Cancer Brain Metastasis.
(2026 Jun 1)
Cancer Res Commun 6(6): 1388-1404
Cheng X, Patel KK, Zhou B, Fu Y, Cleary RT, Highkin M, Hsia J, Jin X, Kohn B, Prior JL, Michie MS, Sun R, Cheng X, Bao L, Heth J, Rastogi T, Van Swearingen AED, Quirk JD, Hagemann IS, Morikawa A, Merrill NM, Merajver SD, Li Q, Schwetye K, Jain V, Gregory SG, Kim AH, Bose R

A pilot randomized controlled trial of an outreach intervention to improve depression treatment initiation among racial and ethnic groups.
(2026 May-Jun)
Gen Hosp Psychiatry 100(): 277-283
Simiola V, Ridout KK, Erickson C, Kazan R, Nie S, Adolfson MP, Simon GE, Miller-Matero LR

Picking Antidepressants-Patient Preferences Beat Biomarkers.
(2026 Apr 14)
JAMA 335(14): 1212-1214
Simon GE

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