Gregory Simon, MD, MPH

Personal Statement

I bring a practical approach to mental health research, working to break down barriers between research and real-world health care.

Education

B.A. Rice University May, 1978
M.D. University of North Carolina May, 1982
M.P.H. University of Washington May, 1990
Intern Internal Medicine University of Washington Hospitals 6/82-6/83
Resident Internal Medicine University of Washington Hospitals 7/83-6/85
Resident Psychiatry Massachusetts General Hospital 7/85-6/88
Fellow Robert Wood Johnson Clinical Scholars Program University of Washington 7/88-7/90

Recent Publications

A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8(+) infiltration in glioma.
(2025 Oct 23)
Sci Rep 15(1): 37112
Singh K, Foster MW, Violette MJ, Corcoran AM, Hotchkiss KM, Railton CO, Blandford EE, Blethen KE, Thomas EL, McIntosh WC, Ashley DM, Desjardins A, Friedman HS, Johnson MO, Friedman A, Keir S, Buckley ED, Herndon JE, McLendon RE, Sampson JH, Calabrese E, López GY, Grant GA, Patel AP, Gregory SG, Li CY, Fecci PE, Khasraw M

Psychiatric Medication Adherence in the United States Before and During the COVID-19 Pandemic.
(2025 Oct)
Pharmacoepidemiol Drug Saf 34(10): e70229
Rossom RC, Yeh HH, Penfold RB, Simon GE, Hooker SA, Ma L, Miller-Matero L, Owen-Smith A, Ahmedani BK

Generative Artificial Intelligence Summaries to Facilitate Emergency Department Handoff.
(2025 Aug)
Appl Clin Inform 16(4): 1185-1191
Genes N, Simon G, Koziatek C, Kim JG, Woo KM, Dahn C, Chan L, Wiesenfeld B

Paired single-cell and spatial transcriptional profiling reveals a central osteopontin macrophage response mediating tuberculous granuloma formation.
(2025 Sep 10)
mBio 16(9): e0155925
Pyle CJ, Wang L, Beerman RW, Jain V, Ohman HKE, Thompson BA, Abramson KR, Ko DC, Gregory SG, Smith CM, Neff JL, Richardson RJ, Stout JE, Tobin DM

Multi-region spatial transcriptomics reveals region specific differences in response to amyloid beta (Aβ) plaque induced changes in Alzheimer's Disease (AD).
(2025 Aug 2)
bioRxiv
Bayaraa O, Aksu M, DeBose-Scarlett E, Hocke E, Jain V, Wang SJ, Cruz D, Gregory SG

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