Gregory Simon, MD, MPH

Personal Statement

I bring a practical approach to mental health research, working to break down barriers between research and real-world health care.

Education

B.A. Rice University May, 1978
M.D. University of North Carolina May, 1982
M.P.H. University of Washington May, 1990
Intern Internal Medicine University of Washington Hospitals 6/82-6/83
Resident Internal Medicine University of Washington Hospitals 7/83-6/85
Resident Psychiatry Massachusetts General Hospital 7/85-6/88
Fellow Robert Wood Johnson Clinical Scholars Program University of Washington 7/88-7/90

Recent Publications

Multi-region spatial transcriptomics reveals region specific differences in response to amyloid beta (Aβ) plaque induced changes in Alzheimer's disease (AD).
(2025 Nov 29)
Hum Genomics
Bayaraa O, Aksu M, DeBose-Scarlett E, Hocke E, Jain V, Wang SJ, Cruz DA, Gregory SG

Lymphotropic Virotherapy Induces DC and High Endothelial Venule Inflammation, Promoting the Antitumor Efficacy of Intratumor Virus Administration.
(2025 Nov 21)
Cancer Immunol Res
Ludwig AL, McKay ZP, Carter GP, Katz MA, Howell G, Jain V, Arvai S, Dittmer DP, Bigner DD, Ashley DM, Shoaf ML, Desjardins A, Gregory SG, Brown MC, Gromeier M

Suicide Prevention Among People of Different Races and Ethnicities in Large Health Systems: Implications for Practice.
(2025 Dec 1)
Psychiatr Serv 76(12): 1066-1073
Coleman KJ, Stewart C, Ahmedani BK, Kahn G, Penfold RB, Frank C, Angerhofer JE, Boggs JM, Sterling S, Yarborough BJH, Clarke G, Schoenbaum M, Aguirre-Miyamoto EM, Barton LJ, Yeh HH, Westphal J, McDonald S, Beck A, Beidas RS, Richardson L, Ryan JM, Buckingham ET 4th, Buttlaire S, Bruschke C, Flores J, Harry ML, Simon GE

A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8(+) infiltration in glioma.
(2025 Oct 23)
Sci Rep 15(1): 37112
Singh K, Foster MW, Violette MJ, Corcoran AM, Hotchkiss KM, Railton CO, Blandford EE, Blethen KE, Thomas EL, McIntosh WC, Ashley DM, Desjardins A, Friedman HS, Johnson MO, Friedman A, Keir S, Buckley ED, Herndon JE, McLendon RE, Sampson JH, Calabrese E, López GY, Grant GA, Patel AP, Gregory SG, Li CY, Fecci PE, Khasraw M

Psychiatric Medication Adherence in the United States Before and During the COVID-19 Pandemic.
(2025 Oct)
Pharmacoepidemiol Drug Saf 34(10): e70229
Rossom RC, Yeh HH, Penfold RB, Simon GE, Hooker SA, Ma L, Miller-Matero L, Owen-Smith A, Ahmedani BK

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