Abigail Schindler, PhD

Personal Statement

I am interested in traumatic stress and its comorbidities (e.g. affective disorders, substance abuse, metabolic dys-function, neurodegeneration). Using an iterative translation approach, we utilize both human and animal populations and focus on reciprocal connections between the brain and peripheral organs (e.g. liver, gut, lymph) in order to under-stand adverse outcomes of traumatic stress from a systems biology standpoint. We are especially interested in under-standing the role of monoamines (e.g. dopamine, seroto-nin) and neuromodulators (e.g. opioids, cytokines). We uti-lize computational medicine approaches (e.g. machine learning, big data, electronic health records, biomarkers) and are committed to open source science.

Department Affiliations

Recent Publications

Repetitive blast mild traumatic brain injury increases ethanol sensitivity in male mice and risky drinking behavior in male combat veterans.
(2021 May)
Alcohol Clin Exp Res 45(5): 1051-1064
Schindler AG, Baskin B, Juarez B, Janet Lee S, Hendrickson R, Pagulayan K, Zweifel LS, Raskind MA, Phillips PEM, Peskind ER, Cook DG

Catecholaminergic Innervation of the Lateral Nucleus of the Cerebellum Modulates Cognitive Behaviors.
(2021 Apr 14)
J Neurosci 41(15): 3512-3530
Carlson ES, Hunker AC, Sandberg SG, Locke TM, Geller JM, Schindler AG, Thomas SA, Darvas M, Phillips PEM, Zweifel LS

Repetitive Blast Promotes Chronic Aversion to Neutral Cues Encountered in the Peri-Blast Environment.
(2021 Apr 1)
J Neurotrauma 38(7): 940-948
Schindler AG, Terry GE, Wolden-Hanson T, Cline M, Park M, Lee J, Yagi M, Meabon JS, Peskind ER, Raskind MM, Phillips PEM, Cook DG

Chronic elevation of plasma vascular endothelial growth factor-A (VEGF-A) is associated with a history of blast exposure.
(2020 Oct 15)
J Neurol Sci 417(): 117049
Meabon JS, Cook DG, Yagi M, Terry GE, Cross DJ, Muzi M, Pagulayan KF, Logsdon AF, Schindler AG, Ghai V, Wang K, Fallen S, Zhou Y, Kim TK, Lee I, Banks WA, Carlson ES, Mayer C, Hendrickson RC, Raskind MA, Marshall DA, Perl DP, Keene CD, Peskind ER

Nitric oxide synthase mediates cerebellar dysfunction in mice exposed to repetitive blast-induced mild traumatic brain injury.
(2020 Jun 10)
Sci Rep 10(1): 9420
Logsdon AF, Schindler AG, Meabon JS, Yagi M, Herbert MJ, Banks WA, Raskind MA, Marshall DA, Keene CD, Perl DP, Peskind ER, Cook DG

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