Abigail Schindler, PhD

Personal Statement

I am interested in traumatic stress and its comorbidities (e.g. affective disorders, substance abuse, metabolic dysfunction, neurodegeneration). Using an iterative translation approach, we utilize both human and animal populations and focus on reciprocal connections between the brain and peripheral organs (e.g. liver, gut, lymph) in order to understand adverse outcomes of traumatic stress from a systems biology standpoint. We are especially interested in under-standing the role of monoamines (e.g. dopamine, serotonin) and neuromodulators (e.g. opioids, cytokines). We utilize computational medicine approaches (e.g. machine learning, big data, electronic health records, biomarkers) and are committed to open source science. Schindler Iterative Translation Lab Website

Department Affiliations

Recent Publications

Impact of Prior History of Traumatic Stress on Autonomic and Multi-System Symptoms Following COVID-19 Infection.
(2025 Jan-Dec)
Chronic Stress (Thousand Oaks) 9(): 24705470251407210
Hendrickson RC, Cheah CS, Tai ML, Pagulayan KF, Liang KJ, McCall CA, Schindler AG, Hart KL, Rosser AF, Oakley JC

Mechanisms Underlying Hazardous Alcohol Use After Mild Traumatic Brain Injury.
(2025)
Alcohol Res 45(1): 09
Patarino M, Sanders J, Schindler AG

Gut Microbial Composition Is Associated with Symptom Self-Report in Trauma-Exposed Iraq and Afghanistan Veterans.
(2025)
Neurotrauma Rep 6(1): 1-12
Li YI, Pagulayan K, Rau H, Hendrickson R, Schindler AG

Neurocognitive Intraindividual Variability in Veterans with Mild Traumatic Brain Injury History and Posttraumatic Stress Disorder.
(2025 Apr 27)
Arch Clin Neuropsychol 40(3): 425-436
Rau HK, Sheppard DP, Karr JE, Hendrickson RC, Schindler A, Peskind ER, Pagulayan KF

Aquaporin-4 mis-localization slows glymphatic clearance of α-synuclein and promotes α-synuclein pathology and aggregate propagation.
(2024 Aug 19)
bioRxiv
Braun M, Simon MJ, Jang J, Sanderson K, Swierz J, Sevao M, Pincus AB, Schaser AJ, Elliott JE, Lim MM, Unni VK, Schindler AG, Keene CD, Latimer CS, Iliff J

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