HIPPOCRATIC App study

The overall goal of this project is to develop a cell phone app that provides continuous assessment of Warfighter health readiness in real time. We are a subcontractor to Warfighter Analytics using Smart Phones for Health (WASH) program and Charles Rivers Analytics for the subject recruitment portion of the overall project.

The UW objective is to recruit 25,000 participants from across the United States to test a newly designed cell phone app named Health & Injury Prediction and Prevention Over Complex Reasoning and Analytic Techniques Integrated on a Cell Phone App (HIPPOCRATIC App) which gathers real-time data measuring an individual’s latent or developing health disorders with a focus on infectious disease and traumatic brain injury. The app is being developed to more effectively assess Warfighter combat/mission readiness and faster, more targeted healthcare delivery for both civilians and Warfighters.

Estia: computerized intervention targeting cognitive control deficits in depressed adults

Project: EVO (or “EVO”) is a mobile 3D video game that has been shown to reduce older adults’ susceptibility to interference by augmenting sustained attention and working memory abilities (e.g. cognitive control) through targeted adaptive algorithms. The combination of peer-reviewed validity, adaptivity, and fun video game mechanics elevates the EVO platform beyond other at-home training tools while reducing burden associated with tedious task replication. We propose to study EVO as a potential intervention for the treatment of depression, a disorder that worsens medical outcomes, promotes disability, increases expense, and complicates medical care by clouding the clinical picture and undermining treatment adherence.

Improving usability

While evidence-based psychosocial interventions (EBPIs) are important, their design is cumbersome, complex, overwhelming, inflexible, and minimizes factors that are crucial for quality delivery of care.

This study will work with six FQHCs across MT that were recently reorganized under Bighorn Valley Health Center’s umbrella to involve their Therapists and Care Managers in the redesign of an intervention to address their unique patient population and to capitalize on their task sharing model.

Project STEP

This project is designed to integrate basic and clinical science to translate mechanisms of recovery from PTSD to testing an intervention in individuals with PTSD and marijuana use. We will recruit 72 individuals with PTSD and varying levels of marijuana use, 36 with current heavy marijuana use and 36 without current marijuana use, to complete a conditional discrimination and extinction task in order to understand the relationship between marijuana and fear learning in individuals with pathological fear. Following this task, participants will receive a brief 6 session imaginal exposure protocol (IE) to explore whether this adapted short form treatment shows increased feasibility (efficacy, reduced drop out) for individuals with co-occurring PTSD and marijuana use. We will also be able to test the link between basic fear and recovery processes by looking at the extinction task as a predictor of treatment response for individuals with and without marijuana use. This research is significant in its potential to identify a predictor of treatment response, to test an underlying mechanism of recovery for PTSD in individuals with PTSD and co-occurring marijuana use, and to test feasibility of a novel intervention for a difficult to treat population.

mHealth Washington

The mHealth Washington team is partnering with 20 community agencies to implement FOCUS in multiple counties throughout Washington State. This implementation effectiveness trial aims to evaluate strategies to integrate mHealth into real-world clinical practice. The team is comprised of multi-discipline experts including academic researchers, policy makers, mental health advocates, Medicaid leaders and individuals with lived experience. 

mHealth in West Africa: developing an evidence-based psychosocial intervention toolkit

There is a shortage of skilled mental health providers in Ghana. Due to the prevalence of traditional faith healers, coupled with the established infrastructure that faith healers in Ghana have, global mental health leaders have argued that these paraprofessionals may be leveraged as conduits of basic illness management strategies.

This study aims to: 1) Employ user-centered mixed-method rapid ethnographic data collection strategies to conduct a targeted needs assessment, and 2) Distill and integrate findings from all data sources to identify content and usability requirements for a human-centered, culturally/contextually-informed multi-media mHealth toolkit for healers.

Mobile RDoC: Using smartphone technology to understand Auditory Verbal Hallucinations (AVH)

Using a mobile data collection system that leverages smartphone technology to capture an abundance of time-varying information both passively (i.e., behavioral sensing) and actively (e.g., Ecological Momentary Assessment or EMA) we aim to: 1) Evaluate whether need for care is associated with real-time/real-place AVH experience; 2) Examine relationships between baseline demographic and functional variables, time-varying social and contextual factors, and AVH; 3) Test relationships posited in a cognitive model of AVH.

Developing a digital training resource for clinicians learning CBT for psychosis (CBTpro)

This project aims to develop and test a digital health resource to provide training and feedback to community mental health clinicians aiming to learn CBT for psychosis (CBTpro). Following the development and iterative testing of the CBTpro prototype, we will recruit 100 community mental health providers and 300 clients with psychosis from two large, publicly-funded community mental health agencies, and randomize them to receive either CBTpro or typical training resources. Following the intervention period, we will examine clinician CBT adherence and competency as well as patient psychotic symptoms.

Pilot study of mHealth for Veterans with serious mental illness

This project aims to examine the feasibility and acceptability of FOCUS, a mobile self-management intervention for individuals with serious mental illnesses. We will recruit 30 veterans receiving services at VA Puget Sound and provide FOCUS for one month, examining feasibility of integrating this intervention into outpatient VA services, acceptability to veterans, and preliminary outcomes including depression, psychotic symptoms, sleep, and recovery.

Developing digital health resources for young adults with early psychosis and their families

This multi-component project aims to (1) gather information about the digital-health related needs, interests, and preferences of young adults with early psychosis and their families, and (2) develop digital health resources that meet those needs. We have collaborated with colleagues to identify interests and needs of family caregivers, and are currently surveying affected young adults. We are also working with a software developer to build a Beta version of a family caregiver-facing mobile health tool providing relevant support and psychoeducation.